Description
Product Characteristics: Synonyms:
MGC138426 antibody,MGC138452 antibody,Parathyroid hormone 1 receptor antibody,Parathyroidhormone/parathyroid hormone related peptide receptor antibody,Parathyroid hormone/parathyroid hormone relatedprotein receptor antibody,Parathyroid hormone/parathyroid hormone-related peptide receptor antibody,PTH receptorantibody,PTH/PTHr receptor antibody,PTH/PTHrP receptor antibody,PTH/PTHrP type I receptor antibody,PTH1receptor antibody,PTH1R antibody,PTH1R_HUMAN antibody,PTHR 1 antibody,PTHR antibody,PTHR1antibody
Target Information: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]